Harrington was inducted into the Hall of Fame alongside 19 time LPGA winner Sandra Palmer as the only two living inductees at the ceremony in North Carolina.
The ceremony also recognised the late LPGA legend Beverly Hanson, former US Open winner Johnny Farrell, and former British Open champion and golf course architect Tom Weiskopf who were inducted posthumously.
In his acceptance speech, Padraig Harrington said that he felt a "deep sense of satisfaction and validation" at his induction into the Hall of Fame.
"Emotionally it brings me deep sense of satisfaction and validation to be inducted into the hall of fame", Harrington said.
He continued: "As a player you get inducted into the hall of fame based on your golf results. So yes, I won three majors, numerous events around the world, I played six Ryder Cups, and that's what gets you in the hall of fame. But there is a story behind it. So what's my story?".
"Firstly I'm not sure whether I loved the game or the game loved me because it was truly great to me", he added. "I loved the fact it was never meant to be a fair game. It was always meant to be a test of skill and mental fortitude. I loved the rules; I loved the etiquette; I loved the competition. Probably ultimately, I loved the meritocracy of it, that you're out there on your own, no one else decides your fate, and it's up to you to get it done".
Elsewhere, Padraig Harrington paid tribute to his long-time caddie Ronan Flood, claiming that he played an integral role in his British Open Championship success in 2007.
"People often ask if caddies really make a difference, and categorically I can say Ronan won me the 2007 Open Championship", Harrington stated. "On the 72nd hole, after I hit my second hole in the water, it was the first and only time I've ever been on the golf course where I felt embarrassed, where I wanted to give up. I really thought I'd thrown away the Open".
"However Ronan stuck to his guns and started into the cliches: 'It's not over yet', 'one shot at a time', and so on", the golfer continued. "I think he took the four iron off me pretty quickly because I'm not sure I wouldn't have had a swing at him with it!".
"But we kept walking, he kept doing his job, and he got in my head. As I walked up to take my penalty drop and by the time I played my fifth shot, I hit it like a teenager. I was right back in the zone".
"I told this story for months afterwards about how my caddie didn't give up on me and how he believed. It took about three months I think before he was in the room and heard me tell this story. He let me tell it, and he stood up at the end, acknowledged that while he'd said all those things, he also thought I'd lost the feckin' Open!".
