The concert is set to air on Virgin Media One this Friday August 27th, at 9pm in aid of The Marie Keating Foundation.
The Marie Keating Foundation confirmed the news, writing: "We can hardly believe we are saying this but we are delighted to announce that @edsheeran has joined the line up for Friday night's #Concert4Cancer! So make sure you tune in at 9pm on @VirginMedia_TV"
The event will also feature performances from Gary Barlow, Anne-Marie, Aslan, The Riptide Movement, and many more.
Concert4Cancer will be hosted by Ronan Keating and Anna Daly and hopes to raise money to support Irish cancer patients.