The 32 year old Dubliner won the first round on all five judges’ cards she got the nod from four of the ringside officials in round 2 which left her in an unassailable position barring a knock-out.
It is the first time Harrington has fought competitively since taking home gold at the Tokyo Olympics.
Meanwhile, Roscommon middleweight Aoife O’Rourke also defeated her Panamanian opponent, Atheyna Bylon, by unanimous decision in the middleweight final.