The couple tied the knot two years ago at Affleck's £7 million home in the southern state of Georgia.
However, reports have suggested that the couple are set to be "pushing ahead with a divorce after a final attempt at reconciliation", according to several sources. Sources have added that divorce documents are to be "finalised, but not yet turned in".
Rumours of the couple's marriage being on the rocks have been gathering pace for months, with Jennifer Lopez previously denying divorce rumours, while promoting her new Netflix movie Atlas in Mexico City without Affleck by her side.
The actress was asked by a reporter, "Is your divorce with Ben Affleck real? These rumours? "What is the truth? Para le press le Mexicana [for the Mexican press], what is the truth of the situation?".
This question was quickly dismissed by Simu Liu, Lopez' co-star, who chimed in with: "Ok, we’re not doing that. Thank you so much guys, we really appreciate it. Thank you".
Jennifer Lopez then remarked: "You know better than that". Liu then added: "Don't come in with that energy please".
Ben Affleck was also a noticeable absentee from Lopez's recent 55th birthday celebrations, which entailed a Bridgerton-themed party.
