The actor who is best known for his role as Mickey Pearce in the British sitcom, revealed the sad news via Twitter, having tweeted that his tumour was shrinking last year.
However, the 66 year old tweeted that "despite all the wonderful efforts" of the staff Guy's, Medway Maritime and King's College Hospitals in the UK, his "lung cancer has returned".
Check out the tweet in full below.
In January 2022, Patrick Murray had revealed that he had undergone an operation to remove a cancerous in its early stages, followed by chemotherapy.
Another tumour was found in further scans, which was unconnected to his lung, but also treatable.